Gout

Question 0

Over production or under excretion of uric acid

Answer 0

Hyperuricemia

Question 1

Gout is deposition of uric acid crystals

Answer 1

Monosodium urate

Question 2

Stage

Abnormally high serum urate level, wala pa itong gouty arthritis

Answer 2

Asymptomatic hyperuricemia

Question 3

Stage

Onset of pain, erythema
First attack

Answer 3

Acute gout

Question 4

90% of acute gour are

Answer 4

Monoarticular

Question 5

Stage

Intervals between attack
Crystals maybe present

Answer 5

Intercritical gout

Question 6

Stage

Large enough of sodium urate to be seen on radiograph

Answer 6

Chronic tophaceous gout

Question 7

Hyper uricemia results primarily from the

Answer 7

Under excretion of uric acid

Question 8

Inhibits xanthine oxidase, resulting in an accumulation of hypoxanthine and xanthine

Answer 8

Allopurinol

Question 9

More soluble than uric acid

Answer 9

Hypoxanthine

Xanthine

Question 10

This enzyme removed amino group from AMP to produced IMP

Answer 10

AMP deaminase

Question 11

IMP nucleoside form

Answer 11

Inosine

Question 12

GMP nucleoside form

Answer 12

GUanosine

Question 13

This enzyme converts IMP and GMP to their nucleoside forms

Answer 13

5 nucleotidase

Question 14

Inosine purine bases

Answer 14

Hypoxanthine

Question 15

Guanosine purine bases

Answer 15

Guanine

Question 16

Enzyme that convert inosine and guanosine to their purine bases

Answer 16

Purine nucleoside phosporylase

Question 17

Guanine is deaminated to form

Answer 17

Xanthine

Question 18

Enzyme used to deaminate gusnine to xanthine

Answer 18

Guanase

Question 19

Hypoxanthine is oxidized by _________ to xanthine

Answer 19

Xanthine oxidase

Question 20

Xanthine to uric acid is also oxidize by

Answer 20

Xanthine oxidase

Question 21

Monosodium urate crystals

Answer 21

Gour

Question 22

Calcium pyrophosphate dihydrate crystals

Answer 22

Pseudo gout

Question 23

Enzyme which further catalyses uric acid to allantoin

Answer 23

Uricase

Question 24

Increased activity of this enzyme can lead to over production of pyrin

Answer 24

PRPP synthetase

Question 25

* reduce the number of white blood cells which travel into the inflamed areas * helps to break the cycle of inflammation, thus reducing swelling and pain

Answer 25

Colchicine

Question 26

* removes the extra uric acid from the body | * helps prevent gout attacks only as long as you continue to take it

Answer 26

Probenecid

Question 27

* used to prevent or treat high uric acid levels in the blood * is a xanthine oxidase inhibitor that works by causing less uric acid to be produced by the body * is also used to prevent or treat high uric acid levels that may be caused by cancer medicines or for patients with kidney stones that contain calcium

Answer 27

Allopurinol

Question 28

is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and help relieve symptoms of arthritis such as inflammation, swelling, stiffness, and joint pain.

Answer 28

Celecoxib