は
Topic particle marks what the sentence is about
Ex: ぼくはアメリカンです
が
Subject particle- marks a word or phrase that is the subject
Ex: だれがアメリカンです
を
Follows a direct object (someone directly affected by the verb)
Indicates a place or object from which someone leaves 八時に家を出る
Place something moves over, along or through はしをわたります
に
2. Location or existence
へ
Motion in general- not used with time words or indicating location