alpha blockers side effects?
Dry mouth Weight gain Dizziness Hypotension Sexual dysfunction
What do alpha 1 blockers do?
reduce smooth muscle tone. treat BPH
What type of cancer is prostate cancer?
Malignant adenocarcinoma
Peripheral zone
Prostate cancer Ix
DRE – hard + irregular PSA (CAUTION: non-specific) Biopsy TRUSS Imaging Bone scan
What grading is used for PC?
gleason score
RCC management?
T1/localised radical nephrectomy Metastatic/non-resectable biological therapies mTOR inhibitors (temsirolimus) TKI (sunitinib, sorafenib) Monoclonal antibodies (bevacizumab)
what can RCC be resistant to?
chemo/radio therapy resistance
Risk factors for bladder cancer?
Occupation – rubber, azo dyes Schistosomiasis (squamous type) Chronic cystitis Pelvic irradiation Lifestyle – smoking Gender – male > female
What is painless haematuria key indicator for?
bladder cancer/ TCC