GU: Premature ejaculation

Question 1

Dapoxetine is what type of drug licensed to be used when required for premature ejaculation (not daily use)?

Answer 1

Dapoxetine is a SSRI, licensed to be used for premature ejaculation.

Question 2

Other selective Serotonin re-uptake inhibitors than dapoxetine have been used off-label for premature ejaculation daily, alongside what other drug?

Answer 2

TCA: amitriptyline.

Question 3

Ejaculaton delay may start a few days after treatment begins but most evident when? why?

Answer 3

1-2 weeks following treatment start as it takes time for receptor desensitisation to occur