Medications that make HF worse
NSAIDs Saxagliptin Sitagliptin Glitazones Ca Channel Blockers Some Antiarrhythmics (disopyramide) Tricyclic antidepressants
Stage A drugs
high risk but no damage or symptoms
ACE I or ARB
Statins
Stage B drugs
Damage but no symptoms
ACE I or ARB (all) Beta Blocker (all)
Statins in patients w h/o MI, ACS
Revascularization
NO CA CHANNEL BLOCKERS
Stage C drugs
Diuretics added to previous regime
ACE I or ARB
Beta Blocker
Add Aldosterone Agonist?
Sacubitril (ARNI)
Angiotensin Receptorblocker / Neprilysin Inhibitor
Sacubitril / Valsartan
Rids Excess Ang II
Hypotension
Dizziness
Cough