What is the Feature of Helicobacter ?
1- Gram-negative bacilli 2- curved ( gullwing appearance ) or spiral , with multiple sheathed 3- monopolar flagella 4- Oxidase positive 5- Microaerophilic 6- highly urease positive 7- causes disease in stomach
Helicobacter can produce ?
protease
What is the toxin of Helicobacter ?
Cytotoxin & Vacuolating toxin
What is the function of Cytotoxin & Vacuolating toxin in Helicobacter ?
=(carcinogenic)→ damage of gastric mucosa
What is the Disease of Helicobacter in the stomach ?
1- Acute gastritis
2- Peptic ulcer (duodenal, gastric)
3- Gastric carcinoma
4- Gastric-MALT lymphoma (B cell lymphoma)
It is a powerful urease producer ?
Helicobacter
highly urease positive ?
Helicobacter
What is the Non invasive diagnosis tests ( no endoscopy ) in Helicobacter ?
1- Urea breath test
2- PCR
3- serological tests