Hematology

Question 1

when would you expect HIT in a patient who was previously unexposed to heparin

Answer 1

if it does develop it’ll be 5-10 days after initial exposure

Question 2

recommended length of AC for 1st episode of DVT (provoked)

Answer 2

3-6 months

Question 3

Deficiency in hemophilia type A

Answer 3

Factor 8

Question 4

lab abnormality in Hemophilia A

Answer 4

• prolonged PTT

Question 5

Treatment for acute bleeding in Hemophilia A

Answer 5

FFP or cryo

Cryo has more Factor VIII

Question 6

Deficiency in Christmas disease

Answer 6

Factor IX

• also known as hemophilia Type B

Question 7

Lab abnormality in Hemophilia Type B

Answer 7

prolonged PTT

Question 8

Treatment for acute bleeding in hemophilia Type B

Answer 8

FFP

Question 9

tests needed to confirm Von Willebrand disease

Answer 9

• Ristocetin-induced platelet agglutination assay
• Plasma Von Willebrand antigen
• Factor VIII levels

Question 10

What glycoprotein is on von Willebrand factor that lets it stick to platelets

Answer 10

glycoprotein Ib

Question 11

how does von willebrand factor interact with platelets to form a clot

Answer 11

allows for platelets to adhere to endothelial injury via glycoprotein Ib on vW factor