What is virchow’s triad
endometrial damage
venous stasis
hypercoaguable
What is involved in the Modified Well’s score
Clinical signs and symptoms of DVT - 3
PE most likely diagnosis - 3
Heart rate >100 - 1.5
Immobilisation >3 days or surgery past 4 weeks - 1.5
Previous PE or DVT - 1.5
Hemoptysis - 1
Malignancy or tx within 6 months - 1
> 4 PE likely
Investigations for DVT
D-dimer - high sensitivity, low specificity
Venous compression US
DVT tx
Apixaban 10mg PO BID x 1 week, then 5mg PO BID
Rivaroxaban 15mg PO BID x 3 weeks then 20mg PO daily
Criteria for lower dose of Apixaban
2/3:f
* age ≥80 years
* body weight ≤60 kg
* serum creatinine ≥133