ALL
immature B/T cells, kid, dx <30% lymphoblasts
AML
immature myeloblasts,
symptoms anemia and ecchymosis dx auer rods
dx<30% myeloblasts
CLL
peripheral BT cells in lymph nodes
hepatosplenomegaly
dx smudge cells
CML
philadelphia chromosome 9/22
sym splenomegaly anemias
dx wbc >50 eosinophils/basophils
Sulfinpyrazone
inhibits degranulation-> prolong platelet survival and inhibit aggregation
dipyridamole
PDE inhibitor- increase cAMP inhibits platelet degranulation
prostacyclin
increases CAMP and inhibits platelet degranulation
antagonist of heparin
protamine sulfate