Which two conditions use hemoglobin (Hb) electrophoresis for diagnosis?
- Thalassemia
- Sickle Cell Disease
How can you differentiate IDA from Thalassemia?
Thalassemia has a normal RDW
- Elevated RDW with IDA
Which condition shows Heinz bodies?
G6PD Deficiency
Which condition shows basophilic stippling?
Lead poisoning
Which three factors are associated with the PT and extrinsic pathway?
- VII
- X
- Tissue Factor
Which four factors are associated with the PTT/aPTT and intrinsic pathway?
- VIII
- IX
- XI
- XII
What is the most common bleeding disorder of childhood?
Idiopathic Thrombocytopenic Purpura (ITP)
Two treatments for Idiopathic Thrombocytopenic Purpura (ITP)?
- Avoid meds that decrease platelet function (i.e. ASA)
- Prednisone
What is the most common inherited bleeding disorder?
Von Willebrand Disease
How can you differentiate vWF Disease from Hemophilia?
Hemophilia has a normal bleeding time
- Prolonged bleeding time for vWF Disease
What is the treatment for vWF Disease and Hemophilia A?
Desmopressin
What condition is triggered by an event?
Disseminated Intravascular Coagulation (DIC):
What is the most common type of small vessel vasculitis?
Henoch-Schönlein Purpura (HSP)
Which condition is preceded by URI; deposition of IgA immune complexes?
Henoch-Schönlein Purpura (HSP)
Which condition has palpable purpura?
Henoch-Schönlein Purpura (HSP)
Which condition involves may develop Warfarin-induced skin necrosis?
Protein C Deficiency
Which condition involves risk of VTE increased dramatically, especially if taking oral contraceptives?
Factor V Leiden
Which condition involves Heparin efficiency significantly diminished?
Antithrombin Deficiency
Which four factors depend on Vitamin K?
- II
- VII
- IX
- X
Which eight factors are synthesized in the liver?
- Prothrombin
- Fibrinogen
- V
- VII
- IX
- X
- XII
- XIII
Which condition involves shock, diffuse bleeding tendency; elevated D-Dimer and fibrin degradation products (FDPs)?
Disseminated Intravascular Coagulation (DIC)
