Hemo Flashcards

(47 cards)

1
Q

Normal CVP/RA range

A

2-6mmHg

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2
Q

Normal PCWP range

A

4-12mmHg

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3
Q

Normal PA range

A

20-30mmHg Systolic
8-15mmHg Diastolic

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4
Q

Normal CO range

A

4-8L/min

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5
Q

Normal CI range

A

2.5-4L/min/M2

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6
Q

What is Hypervolemia

A

Increased CVP, PAP, PCWP, BP, and SVR
Normal or Increased CO

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7
Q

Treatment on Hypervolemia

A
  • Treat primary cause (failing organ(
  • Diuretics
  • Limit fluid administration
  • Dialysis
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8
Q

What is vasoconstriction

A

Increased PCWP, SVR, BP (!), CVP, PAP
Decreased or normal CO
BP critical range, >180 systolic and >98 diastolic

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9
Q

Treatment of vasoconstriction

A
  • Direct Vasodilators: Nitroprusside, Hydralazine, Milrinone
  • ACE inhibitors: Lisinopril, Perindopri
  • Calcium Channel blockers: Amlodipine
  • Beta Blockers to decrease HR: propranolol
  • Diuretics
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10
Q

What is hypovolemia?

A

Decreased BP, CVP, PAP, PCWP, CO
Increased SVR

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11
Q

Treatment for hypovolemia

A

-IV fluids, NaCL or blood
- stop the cause of fluid loss
- Vasopressors to increase BP (epi, dopamine, etc.)

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12
Q

What is vasodilation?

A

Decreased BP, CVP, PAP, PCWP, SVR
increased CO

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13
Q

Treatment of vasodilation

A

Give vasopressors
Give IV fluids
Oxygen
Anticoagulants

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14
Q

What is LVHF

A

Increased: PCWP, SVR, CVP and PAP
Decreased: CO, BP

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15
Q

Treatment of LVHF

A
  • Inotropic agents to increase contractility, dopamine, noreepi
    Diuretics
    Oxygen
    PEEP
    analgesics
    Anticoagulants
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16
Q

Cardiogenic Shock

A
  • R or L heart dysfunction cause by MI, arrhythmias or cardiac myopathy
  • Cool clammy, cyanotic, AMS, decrease urine output
    Increased: CVP, PAP, SVR
    Decreased: BP and CO
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17
Q

Treatment for cardiogenic shock

A

Inotropic agents: dopamine
Diuretics
Oxygen
PEEP
analgesics
Anticoagulants

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18
Q

Hypovolemic shock

A

Loss of intravascular fluid cause by:
- Bleeding
- Excessive diarrhea or vomiting
- Wounds or burns
- Ruptured vessel
- Third spacing

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19
Q

Hemodynamics of hypovolemic shock

A

Decreased BP, CVP, PAP, PCWP, CO
Increased: SVR

20
Q

Treatment of Hypovolemic shock

A

Fluid resuscitation
Vasopressors
Lie flat and elevate feet
Keep warm
Oxygen

21
Q

Neurogenic shock

A

C-spine or upper thoracic spine injury (C5 and higher) which causes damage to the SNS system. Drop in HR, BP, and inadequate control of body temp

22
Q

Hemodynamics of neurogenic shock

A

Decreased CVP, HR, BP, SVR, CO, PCWP, CVP

23
Q

Treatment of neurogenic shock

A

Fluid resuscitation
Vasopressors
Epinephrine
Atropine to increase HR
Stabilize neck
Maintain airway and breathing
Oxygen
Anticoagulants

24
Q

Anaphylactic shock

A

Hypersensitivity to an allergen which causes a release of histamine. Massive vasodilation and capillary leaking which causes edema and swelling

25
Hemodynamics of anaphylaxis
Increased HR, CO Decreased BP, SVR (!), PCWP, CVP, PAP
26
Treatment of anaphylactic shock
Epinephrine Fluid resuscitation Racemic epinephrine for stridor Albuterol for wheezing ICS for inflammation
27
Septic shock and the hemodynamics of it
Systemic inflammatory response to an infection Decreased BP, SVR, PCWP, CVP, PAP Increased HR
28
Treatment of septic shock
Give antibiotics Remove sources of possible infection Give vasopressors Fluid resuscitation Antipyretics for fever as indicated
29
ECMO
A short term treatment which provides aggressive form of life support for people with heart or lung failure (or both). The blood is oxygenated and CO2 is removed outside of the body through a membrane oxygenated It’s use is diminishing with the increase of HFJV, HFOV, or iNO
30
VA ECMO
Veno-Arterial. Blood is drawn from the right atrium via the internal jugular vein Oxygenated blood is returned to the aortic arch via the right common carotid artery Typically used with cardiac failure or a bridge to a heart transplant
31
VV ECMO
Veno-venous. Blood is removed from the right atrium from the right internal jugular vein Blood is returned to the right atrium via the femoral vein Used for acute respiratory failure or a bridge to lung transplant
32
33
Indications for ECMO
OI >25 or P/F ratio <100 Failed conventional therapy methods Patient has a reversible disorder Patient has not suffered at ICH or stroke
34
Hazards/complications of ECMO
ICH Clots Medication deposits in PVC tubing Bleeding secondary to heparin Infection Equipment related malfunctions
35
CvO2 formula
(Hb x 1.34 x SvO2) + (PvO2 x 0.003)
36
Normal PvO2
35-45mmHg
37
Normal SvO2
75%
38
Normal CvO2
15 vol%
39
CcO2 definition and equation
assumes 100% saturation in pulmonary capillary blood Used to calculate pulmonary shunting and evaluate oxygenation efficiency (Hb x 1.34 x 1.0) + (PAO2 x 0.003)
40
Low SvO2 and High SvO2 meanings
Low: Decreased O2 delivery or increased female (anemia, hypovolemia, low CO, hypoxia) High: Decreased Tissue O2 use (sedation, sepsis, hypothermia, shunting)
41
CaO2 definition and equation
The arterial oxygen content reflects how much oxygen is available to the tissues (Hb x 1.34 x SaO2) + (PaO2 x 0.003)
42
DO2
Total oxygen delivery Normal: 900-1200 mL/min Decreases with low oxygenation low hemoglobin and decreased CO Increases with improved oxygenation, hemoglobin, or cardiac output
43
C(a-v)O2
Represents the amount of oxygen extracted by the tissues Increased difference: Decreased cardiac output, or increased O2 Decreased difference: Increased CO, peripheral shunting, sepsis, hypothermia
44
Oxygen Consumption (VO2)
Amount of oxygen used by the tissues each minute (oxygen uptake) Increased VO2: exercise, seizures, shivering, hyperthermia Decreased VO2: sedation, hypothermia, sepsis, cyanide toxicity
45
Oxygen extraction ratio
O2ER = (CaO2 - CvO2) / CaO2 x 100 Normal: 25% Indicates the proportion of delivered oxygen extracted by the tissues Increased: Low CO, anemia, increased metabolism Decreased: High CO, Sepsis, Hypothermia, cyanide toxicity
46
What is pulmonary shunting? What are the 3 categories?
A shunt is the portion of cardiac output that moves from the right to the left heart without exposure to alveolar oxygen (PAO2) 1. Absolute (true) shunt 2. Capillary shunt 3. Relative shunt (shunt-like effect)
47
Shunt clinical significance
<10% normal 10-20% intrapulmonary shunting 20-30% significant disease >30% Life threatening