Inhibits formation and activation of replication complex
Inhibition of NS4A
Enzyme responsible for cleaving and processing polypeptide
NS3/4A
Pol that mediates HCV RNA replication
NS5B
Important in replication, assembly, and secretion
NS5A
Booster for paritaprevir
CYP3A4
Essential substrate for viral RNA synthesis
Inosine monophosphate dehydrogenase
Inhibits viral RNA replication and vision assembly
Inhibition NS5A