Anticoagulants > Heparin > Flashcards

Heparin Flashcards

(5 cards)

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1
Q

Examples

A

LMWH
(Enoxaparin)
UFH (Unfractionated)

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2
Q

MoA

A

Anti-thrombin III (ATIII) - Serine protease inhibitor
Agonist
Heparin-ATIII complex inactivates thrombin (IIa) + Xa (UFH)
Inhibits coagulation cascade

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3
Q

Indications

A

Prevention + Tx of Thromboembolic disease
Prophylaxis DVT
Acute MI

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4
Q

ADR

A

Bleeding (- protamine sulphate)
Hyperkalaemia
(hypoaldosteronism)
Thrombocytopenia

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5
Q

Prescribing Advice

A

IV Administration
Monitoring of activated partial thromboplastin time (APTT)
X Renal failure

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Anticoagulants
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