hepatic dysfunction

Question 1

what is child pugh score whats looked at

Answer 1

used to assess the severity of liver disease, C being decompensated and severe
bilrubin

Question 2

signs of liver disease

Answer 2

clubbing jaundice ascites peripheral oedema spider naevi

Question 3

medicatons causing liver issues

Answer 3

fluclox co amox nsaids metho amiodarone

Question 4

antidote for paracetamol

Answer 4

acetylcysteine

Question 5

two basic principles of metabolism

Answer 5

phase 1 - oxidation, reduction or mehtylation - p450

phase 2 - conjugation - making it more water soluble

Question 6

caution in liver disease

Answer 6

encephalopathy
clotting abnormalities
consider which drugs can contribute towards

Question 7

what can collateral shunts cause

Answer 7

decrease in first pass metabolism due bypassing the liver

Question 8

does diclofenac induce liver enzymes

Answer 8

no

Question 9

do you assess risk factors before acetylcysteine

Answer 9

no