Pathophysiology > Hepatitis > Flashcards

Hepatitis Flashcards

(15 cards)

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1
Q

hepatitis

A

Inflammation of the liver

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2
Q

causes

A

Viruses, alcohol, autoimmune disease

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3
Q

Hepatitis A

A

Caused by the hepatitis A virus– transmitted
through ingestion of fecal matter containing the
virus

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4
Q

Hepatitis B

A

Caused by the hepatitis B virus – transmitted
through contact with infected body fluids (blood,
semen). Can also be transmitted from a mom to
baby during childbirth

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5
Q

Hepatitis C

A

caused by the hepatitis C virus – transmitted
through blood contact from shared needles or
improper sterilization of healthcare tools

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6
Q

Hepatitis D

A

Caused by the hepatitis D virus– cannot cause
infection on its own, only develops in people
already infected with the hepatitis B virus

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7
Q

Hepatitis E

A

Caused by the hepatitis E virus– transmitted
through the consumption of contaminated water
or food.
chronic

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8
Q

ssRNA types

A

Types A, C, E, D

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9
Q

ssRNA steps 1 and 2

A

1.Virus enters through endocytosis and releases RNA

  1. RNA goes to the host cell ribosome to synthesize proteins
    -makes capsomeres, antigens, and
    RNA polymerase
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10
Q

ssRNA steps 3 and 4

A
  1. Proteins go to the golgi and are packaged in vesicles
  2. RNA polymerase increases RNA production to combine with proteins to form
    viruses
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11
Q

dsRNA type

A

type B

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12
Q

dsDNA step 1

A

Virus enters hepatocyte and releases DNA into nucleus

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13
Q

dsDNA step 2-4

A
  1. DNA can use cell RNA polymerase to make viral RNA
  2. RNA can make mRNA to make more proteins in ribosome
  3. RNA can use reverse transcriptase enzyme to make DNA
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14
Q

dsDNA steps 5-6

A
  1. DNA combines with proteins in vesicles to form virus
  2. Viral DNA uses host DNA polymerase to keep self-replicating
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15
Q

Chronic hepatitis

A

-Down regulate T cell response
-surface antigen wins over IgG
antibodies
-dsDNA self-replicating

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