Hepatitis

Question 1

Alcoholic Hepatitis MOA?

Answer 1

MOA: Acetaldehyde mediates damage

Question 2

What are mallory bodies?

Answer 2

Damaged Intermediate filament (damaged keratin filaments)

Question 3

Non-Alcoholic fatty liver disease MOA? Associated with and Not associated with?

Answer 3

Insulin resistance=>fat going into cells=>cells die/balloon

No Alcohol association

associated with obesity

Question 4

Hepatocellular carinoma=> 3 important causes; serologic marker to look for?

Answer 4

Alfatoxin with Aspergillus
Hemochromatosis
Wilson Disease

AFP elevated

Question 5

Hepatic adenoma is associated with?

Answer 5

OCP use

Question 6

Budd-Chiari is? What is important to remember?

Answer 6

Blockage of hepatic vein=>congestive liver disease

Absence of JVD and Increased AFP