HepBsAg +
Anti-HBs -
Infected
HepBsAg -
Anti-HBs +
Immune due to vaccine
Hepatitis B e antigen (HBeAg)
Marker of HBV replication and infectivity.
Presence is associated with high levels of HBV DNA in serum and higher rates of vertical transmission
Risk of vertical transmission Hep B?
From HBsAg + mothers to infants is as high as 90% without active (vax) and passive (HBIG) immunization
Maternal screening:
Testing for HBsAg should be performed on all women at the first prenatal visit
The principal risk factors for HCV transmission?
IV drug abuse
Blood transfusion
Risk of vertical transmission Hep C?
5%
25% when co-infection with HIV