Heritability

Question 1

Relative of people with affective disorders are __X’s more likely to develop affective disorders than relative of people who do not have AD

Answer 1

10 times!!! I don’t care

Question 2

Twin studies

Answer 2

1. 70% concordance rate of affective disorder for monozygotic twins
   - whether raised together or apart
2. 13% concordance rate for dizygotic twins

Question 3

Multiple genes have been found to be related to affective disorders but results were not replicated

Answer 3

1. Recent findings indicate 5HT transporter gene on chromosome 17 has important influence on depression – but meta-analysis found no significant effects for this gene
2. Review of genome-wide association studies found RORA gene chromosome 15 involved in circadian rhythms has strongest association with depression