Triad of paroxysmal nocturnal hemoglobinuria
DX and TX
DX: flow cytometry, ACQUIRED SC mutation
Tx Eculizumab
What is Plummer-Vinson syndrome
dysphagia + esophageal webs + atrophic glossitis + Fe def.
What is SIADH and what electrolyte abnormalities are a result
excess ADH–> free water retention–> impaired water excretion
Treatment of:
CXR: honeycombing, diffuse reticular opacities, ground glsas
idiopathic pulmonary fibrosis
-restrictive pattern
Describe findings of Obstructive shock
Describe hypertrophic cardiomyopathy murmur changes with different positions
What is Wegners
small vessel vasculitis w/ granulomatous inflammation and necrosis of nose, lungs and kidneys
+C-ANCA
TX: corticosteroids + cyclophosphamide
Clinical manifestations of DI
SE of phenytoin
SE of Lithium
Tamoxifen vs Raloxifene
Tamoxifen (E. antagonist of breast and uterus)
Raloxifene (E. antagonist of breast)
CXR: pleural plaques/thickening, intersitital fibrosis, MC in lower lobes
asbestosis
Describe findings of Septic shock
(type of distributive shock)
Tx of Rheumatic fever
2. PCN G
CXR: peribronchial fibrosis, bronchial wall thickening, “tram track” bronchials,
bronchiectasis
*foul smelling sputum, hemoptysis
MC- H. influenza, if CF= pseudomonas
Trichinosis
TX: self limiting–> albendazole if severe
Sx of anterior cerbral artery stroke
SE of 2nd generation antipyschotics agents
dopamine antagonist and serotonin antagonist
HIV drug SE
What vaccines are contraindicated with:
MOA and SE of thiazolidinediones (pioglitazone, rosiglitazone)
MOA: increased insulin sensitivity at peripheral receptor site
Uses of carbamazepine
seizures, bipolar, trigeminal neuralgia, Central DI
TX of central DI
2. carbamazepine