HIT

Question 1

Type 1

Answer 1

Nonimmune
1-4d after heparin therapy
Plt > 10,000/uL, 
No sequelae
Can continue heparin and observe

Question 2

Type 2

Answer 2

Actually called HIT
Immune IgG mediated
After 4-10 days, can occur within 24 hrs if prior exposure within 100days
Plt 60,000/uL, 50% plt reduction
Thrombotic events in 30-50%
Need to discontinue heparin, alternative anticoagulation