HIV

Question 1

step 1 of HIV cycle and drug
step 2 of HIV cycle and drug
step 3 of HIV cycle and drug
step 4 of HIV cycle and drug
step 5 of HIV cycle and drug
step 6
step 7

Answer 1

1. Binding & attachment
   maraviroc (Selzentry) - CCR5 antagonist
   attachment inhibitor- fostemsavir (Rukobia)
2. Fusion: fusion inhibitor enfuvirtide (Fuzeon)
3. Reverse Transcription - NRTI/NNRTI
4. Integration - INSTI
   5.
   6.
5. Budding & maturation- protease inhibitor

Question 2

what are routine labs for indication of immune response

Answer 2

CD4
HIV viral load - want undetectable load
genotype testing
Hep B & C screening
pregnancy
HLA-B- 5701 allele or tropism assay for maviroc