Hormone Patterns

Question 1

Primary hypogonadism

Answer 1

H FSH
H LH
L Testosterone
~ Prolactin
Causes: testicular failure, ovarian failure

Question 2

Secondary hypogonadism

Answer 2

L FSH
L LH
L Testosterone
~ Prolactin (H if pituitary adenoma)
Causes: pituitary or hypothalamic dysfunction

Question 3

Hyperprolactinaemia

Answer 3

L FSH
L LH
L Testosterone
H Prolactin
Causes: prolactinoma. Prolactin suppresses GnRH

Question 4

Klinefelter

Answer 4

H FSH
H LH
L Testosterone
~ Prolactin
Causes: 47XXY

Question 5

Androgen Insensitivity

Answer 5

H FSH
H LH
H Testosterone
~ Prolactin

Ineffective testosterone

Question 6

PCOS

Answer 6

Raised LH:FSH
~/ (mild) H Testosterone
~/H Prolactin

Question 7

CAH

Answer 7

L FSH
L LH
H Testosterone
~ Prolactin

Question 8

Kallman

Answer 8

L FSH
L LH
L Testosterone
~ Prolactin
Causes: congenital GnRH deficiency. Anosmia.