HUS

Question 1

What is the triad of symptoms of haemolytic uraemia syndrome?

Answer 1

• haemolytic anaemia (normocytic anaemia)
• thrombocytopenia
• AKI

Question 2

What is HUS?

Why does it cause the symptoms that it does?

Answer 2

Thrombosis in small blood vessels

• platelets get caught up in clots -> thrombocytopenia
• gets clogged up in small blood vessels in kidney -> AKI

Question 3

It will occur following what?

Answer 3

5-7 days following period of gastroenteritis

Question 4

What causes HUS?

Answer 4

Shiga toxin

from E.Coli 0157 + shigella

Question 5

How is it managed?

Answer 5

Supportive management however it is a medical emergency and requires patients to be under observation

Question 6

What may occur dermatologically due to thrombocytopenia?

Answer 6

Bruising