Hyperandrogenism

Question 1

What is the difference between hirsutism and virilization?

Answer 1

Hirsutism: presence of masculine hair growth.

Virilization: Development of male features ( voice, increased muscle mass, clitoromegaly, etc..)

Question 2

What is Cushing syndrome? What is the most common cause?

Answer 2

Excess production of Cortisol, Cushing disease.

Question 3

How is polycystic ovarian syndrome diagnosed?

Answer 3

Two out of three Rotterdam Criteria :
1. Oligomenorrhea or Anovulation
2. Hyperandrogenism
3. Polycystic ovaries

Question 4

What can explain hirsutism In idiopathic hirsutism?

Answer 4

Increased activity of 5a-reductase at the level of the skin and hair follicles.

Question 5

What happens to SHBG in PCOS?

Answer 5

Increased level of Sex Hormone Binding Globulins