Hyperlipidaemia

Question 1

History for hyperlipidaemia

Answer 1

1. Family Hx
2. CVD risk - Hx, CDV, DM, HTN, Smoker, increased BMI, low SES
3. Age diagnosed
4. treatments used
5. diet and exercise

Question 2

Investigations

Answer 2

Bloods - to establish what lipids are raised (eg, hypertriglyceridaemia or hypercholerterolaemia)

• Creatinine Kinase - after starting statin
• LFTs - to look for FLD and for statin derrangement

Question 3

Management:

Answer 3

Lifestyle - reduce BMI, reduce saturated fats, increase fruit and vegetables and increase exercise

Medications:

1. Statins (40mg simvastatin) reduces cholesterol synthesis in the liver
2. Fibrates (bezafibrate - useful in mixed hyperlipidaemia and hypertrigluceridemia) or cholerterol absoprtion inhibitors (eg. ezetimibe)