Patient demographic of HHS
T2DM
Older
Long history (eg. 1 wk)
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Pathophysiology of HHS
Dehydration
Hyperglycaemia > 35 mM
Osmolality > 340 mosmol/kg
No acidosis (no ketogenesis)
Complications of HHS
Occlusive events - DVT, Stroke
Give LMWH
Mx of HHS
Saline over 48 hrs - may need 9L
Wait 1 hr before starting insulin - may not be needed, start slow
Look for precipitant - MI, infection, bowel infarct