Hypersensitivity is
Host tissue damage / irritation
Innate defences
First line of defence
Complement system
Neutrophils , basophils, eosinophils , macrophage
Hypersensitivity 1
Allergy anaphylaxis atrophy
Response in minutes
Hypersensitivity 2
Antonody IGM IGG
Hypersensitivity 3
Complex mediated
Hyper 4
Delayed - CD4 cd8
Chemokine killing
Hall marks of type 1
IGE production activation of TH2 cells
Characteristics of allergic reaction.
Repeatedly exposed to them
Don’t include macrophages or dendritic cells