Paediatrics > IBD > Flashcards

IBD Flashcards

(21 cards)

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1
Q

What are the differences in presenting features between UC and Crohn’s?

A

Weight loss and growth failure more common in Crohn’s

Diarrhoea and rectal bleeding more common in UC

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2
Q

What are some extraintestinal features of IBD?

A
  • Erythema nodosum
  • Oral changes
  • Perianal changes
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3
Q

Which blood investigations are carried out for IBD?

A

Full blood count & ESR

  • Anaemia (mainly Crohn’s)
  • Thrombocytosis
  • Raised ESR
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4
Q

Which biochemical tests are carried out for IBD?

A

•Stool calprotectin

  • Raised CRP
  • Low Albumin (leaking protein into gut, tends to be Crohn’s but sometimes acute severe colitis)
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5
Q

What microbiological tests are carried out to diagnose IBD?

A

No stool pathogens

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6
Q

What are the differences between IBD presentation in children and adults?

A
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7
Q

How does incidence of proctitis in child UC patients differ from that of adults?

A

Typical presentation for adults

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8
Q

How does incidence of left-sided colitis in child UC patients differ from that of adults?

A

Typical presentation for adults

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9
Q

How does incidence of pancolitis in child UC patients differ from that of adults?

A

PANCOLITIS -> CHILD!!

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10
Q

How does incidence of isolated ileal inflammation in a child Crohn’s patients differ from that of adults?

A
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11
Q

How does incidence of illeocolonic inflammation in a child Crohn’s patients differ from that of adults?

A

Almost even

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12
Q

How does incidence of upper GI/panenteric inflammation in a child Crohn’s patients differ from that of adults?

A
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13
Q

What are the defintive radiological IBD investiagtions?

A

(especiallyCrohn’sdisease)

  • MRI
  • Barium meal and follow-through (younger kids)
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14
Q

What are the definitive endoscopic investigations in IBD?

A
  • Colonoscopy & Upper GI endoscopy
  • Mucosal biopsy
  • Capsuleenteroscopy
  • Enteroscopy
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15
Q

What are the aims of IBD treatments?

A
  • Induce and maintain remission
  • Correct nutritional deficiencies
  • Maintain normal growth and development
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16
Q

What are the pharmacological treatments of IBD?

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A
  • Anti-inflammatory
  • Immuno-suppressive
  • Biologicals (Infliximab)
17
Q

What are the nutritional treatments for IBD?

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A
  • Immune modulation
  • Nutritional supplementation
18
Q

What other way can IBD be treated?

19
Q

When might you use surgery before biologics?

Study These Flashcards
A

In isolated disease

20
Q

Describe the escalation of IBD treatment?

Study These Flashcards
A

Azathioprine - immunosuppressant

MP - mercaptopurine

21
Q

What factors point to diagnosis of IBD?

Study These Flashcards
A
  • History & Examination
  • Intestinal symptoms
  • Extra-intestinal manifestations
  • Exclude infection
  • Family History
  • Growth and sexual development - particularly Crohn’s
  • Nutritional status
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