IBS

Question 1

Patho

Answer 1

-chronic abdominal pain and altered bowel habits in absence of any organic cause
uncertain may be due to:
- GI motility
- visceral hypersensitivity
- inflammation
- food sensitivity
- bacterial overgrowth

Question 2

definition

Answer 2

recurrent abdominal pain or discomfort on avg, at least 1 day per week in last 3 months with 2 or more of following:

• improvement with defecation
• change in stool frequency
• change in stool form

Question 3

IBS with constipation

Answer 3

abnormal bowel movement, usually constipation

Question 4

IBS with diarrhea

Answer 4

abnormal bowel movement, usually diarrhea

Question 5

Mixed IBS

Answer 5

abnormal bowel movements are both constipation and diarrhea

Question 6

Unclassified IBS

Answer 6

patients who meet diagnostic criteria for IBS but can’t be accurately categorized

Question 7

Indications for endoscopic evaluation

Answer 7

• more than minimal rectal bleeding
• weight loss
• unexplained iron deficient anemia
• nocturnal sx
• FHx of colorectal cancer, IBD, celiac sprue

Question 8

Tx

Answer 8

dietary modification
- low gas-producing food
- lactose avoidance
- low fodmap diet: fermentable foods
- gluten avoidance
physical activity
IBS constipation- Lubiprostone and Linaclotide