Ibuprofen drug class
NSAIDS
Ibuprofen brand names
Motrin, Advil
Ibuprofen indications (OTC)
Pain, headache, fever
Ibuprofen indications (Rx)
Osteoarthritis or rheumatoid arthritis, Juvenile rheumatoid arthritis
Ibuprofen mechanism of action
Non-selective inhibitor of COX1 and COX2. Reversibly alters platelet function and prolongs bleeding time
Ibuprofen contraindications
Hypersensitivity, Aspirin Triad: Asthma, Urticaria, or allergic type reactions. CABG surgery, treatment of perioperative pain.
Ibuprofen black box warning
Cardiovascular events, GI toxicity, CABG
Ibuprofen adverse drug reactions
More than 10% unknown, less common of GI distress, edema, itching, rash, dizziness, tinnitus, toxicity.
Ibuprofen serious adverse drug reactions
SJS, GI bleeding, thrombosis, elevated LFTs, acute renal failure, congestive heart failure, aplastic anemia
