ICS

Question 1

main indications

Answer 1

second line in asthma
consider for COPD where patient is a frequent exacerbator

Question 2

mechanism of action

Answer 2

• reduce airway inflammation by increasing transcription of genes encoding anti-inflammatory proteins and decreasing transcription of genes encoding inflammatory proteins

Question 3

contraindications and cautions

Answer 3

few absolute contraindications

Question 4

adverse effects

Answer 4

• dysphonia and oropharyngeal candidiasis
• may cause pneumonia in COPD due to local immune suppression and impaired mucociliary clearance

Question 5

administration

Answer 5

inhaler