1
Q
Which enzymes catalyse formation of components of the fungal cell wall?
A
Synthase enzymes
2
Q
What is the main sterol in fungi?
A
Ergosterol
3
Q
Which enzyme do allylamines inhibit?
A
Squalene epoxidase
4
Q
What do azoles inhibit?
A
Cytochrome P450 14-DM
5
Q
How is AMB (Amphotericin B) infused?
A
IV, every 48-72 hours until total cumulative dosage has been reached
6
Q
What form the structural basis of a fungal cell wall?
A
Cross-linked glycoprotein, glucan and chitin
Year 2 Semester 2
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