Risk of sepsis in cohort of 8000 asplenic patients over 27 years?
RR of sepsis 3.4
RR of sepsis related mortality 3
What is MIC (minimum inhibitory concentration) and how it correlates with sensitive/intermediate/resistant determination?
MIC number is the lowest concentration of antb that inhibits that strain of bacteria (in mcg/mL)
Sensitive- inhibited by serum concentration achieved by typical dosing
Intermediate - organism inhibited by only maximal recommended dosages