ID coverage objective

Question 1

Methicillin-resistant Staphylococcus aureus (MRSA)

Answer 1

• Teflaro (ceftaroline)
• Delafloxacin
• Tetracyclines (CA) + derivatives
• *Bactrim
• *Monurol (fosfomycin)
• Rifampin
• Bactroban (mupirocin)
• *Cleocin (clindamycin)
• Cubicin (daptomycin)
• Zyvox (linezolid)
• From bug drug chart: Ceftaroline, All glycopeptides, lipoglycopeptides, and lipopeptides, Streptogramins, Bactrim, Fosfomycin

Question 2

Pseudomonas aeruginosa

Answer 2

• Zosyn
• Maxipime (cefepime)
• Cipro
• Levofloxacin
• Delafloxacin
• *Monurol (fosfomycin)
• *Carbapenems (not ertapenem)
• From bug drug chart: Ticarcillin, Piperacillin, Ceftazidime/avibactam, Ceftolozane/tazobactam, Aztreonam, Fosfomycin, Ciprofloxacin, Aminoglycosides, Colistin

Question 3

Vancomycin-resistant enterococcus (VRE)

Answer 3

• *Monurol (fosfomycin)
• Cubicin (daptomycin)
• Zyvox (linezolid)
• From bug drug chart: Quinupristin/dalfopristin, Nitrofurantoin, Tetracycline derivatives

Question 4

Anaerobes

Answer 4

• *Unasyn
• Zosyn
• Avelox (moxifloxacin)
• Flagyl (metronidazole)
• *Cleocin (clindamycin)
• *Carbapenems
• From bug drug chart: Ticarcillin, Amoxicillin-Clavulanate, Cefoxitin, Ceftriaxone, Cefotaxime, Ceftolozane/tazobactam, Tetracycline derivatives

Question 5

Atypicals

Answer 5

• *Macrolide
• Tetracyclines + derivatives
• Fluoroquinolones (Cipro, Levofloxacin, Moxifloxacin, Gemifloxacin, Delafloxacin)

Question 6

Extended spectrum beta lactamases (ESBLs)

Answer 6

• *Monurol (fosfomycin)
• *Carbapenems
• From bug drug chart: Aztreonam, Ceftolozane/tazobactam, Cefepime, Piperacillin-Tazobactam, Colistin, Tetracycline derivatives, Plazomicin (other aminoglycosides as empiric), Fluoroquinolones)