ILCs

Question 1

What are the cytotoxic ILCs and what are they involved in?

Answer 1

• NK cells

- Involved in immunity to viruses and cancer, and chronic inflammation

Question 2

What are the non-cytotoxic ILCs?

Answer 2

• ILC1s
• ILC2s
• ILC3s

Question 3

What are the main functions of the ILC1s?

Answer 3

• Immunity to intracellular bacteria and protozoa and chronic inflammation

Question 4

What are the main functions of the ILC2s?

Answer 4

• Immunity to helminths
• Asthma and allergic diseases
• Metabolic homeostasis

Question 5

What are the main functions of ILC3s?

Answer 5

• Lymphoid tissue development
• Intestinal homeostasis
• Immunity to extracellular bacteria
• Role in chronic inflammation