Immunization

Question 1

Examples of live attenuated vaccines

Answer 1

MMRV, rotavirus, oral polio, BCG, oral typhoid

Question 2

If a live vaccine is given first, it is necessary to wait __ before giving an antibody

Answer 2

2 weeks

Question 3

Interval between hepatitis A/B prophylaxis and live vaccine

Answer 3

3 months

Question 4

Interval between standard measles prophylaxis and live vaccine is __; for immunocompromised __

Answer 4

standard - 5 months

immunocompromised - 6 months

Question 5

Interval between rabies prophylaxis and live vaccine

Answer 5

4 months

Question 6

Interval between tetanus prophylaxis and live vaccine

Answer 6

3 months

Question 7

Interval between IVIG and live vaccine for:

1. replacement therapy of immune deficiencies
2. ITP 400 mg/kg
3. ITP 1000 mg/kg
4. varicella postexposure prophylaxis
5. Kawasaki disease

Answer 7

1. Immune deficiency - 8 months
2. ITP 400 - 8 months
3. ITP 1000 - 10 months
4. varicella - 8 months
5. Kawasaki - 11 months

Question 8

Interval between washed pRBC and live vaccine

Answer 8

none

Question 9

Interval between pRBC and live vaccine

Answer 9

6 months

Question 10

Interval between whole blood and live vaccine

Answer 10

6 months

Question 11

Interval between plasma or platelet products and live vaccine

Answer 11

7 months

Question 12

Examples of inactivated whole-cell viral vaccines

Answer 12

polio, hepatitis A, rabies

Question 13

Examples of inactivated whole-cell bacterial vaccines

Answer 13

pertussis, cholera

Question 14

Examples of fractional vaccine subunits

Answer 14

hepatitis B, influenza, acellular pertussis, HPV

Question 15

Examples of fractional vaccine toxoids

Answer 15

diphtheria, tetanus

Question 16

Examples of pure polysaccharide vaccines

Answer 16

pneumococcal, meningococcal, typhoid

Question 17

Examples of conjugated polysaccharide vaccines

Answer 17

HiB, pneumococcal, meningococcal

Question 18

Examples of inactivated, genetically engineered recombinant vaccines

Answer 18

hep B, HPV

Question 19

Two exceptions to no interval between inactivated vaccine administration and simultaneous vaccine administration:

Answer 19

1. Tdap and MCV4 (at least 4 weeks if not simultaneous)

2. yellow fever vaccine and cholera vaccine (at least 3 weeks)

Question 20

2 permanent contraindications to further doses of a vaccine

Answer 20

1. severe anaphylactic reaction

2. encephalopathy not due to another identifiable cause occurring within 7 days of a pertussis vaccination

Question 21

Two conditions that are temporary contraindications to live vaccines

Answer 21

1. pregnancy
2. immunosuppression

• asymptomatic HIV may receive live vaccines

Question 22

A history of GBS is a precaution for which vaccines

Answer 22

tetanus-containing
influenza
meningococcal conjugate

Question 23

Permanent precautions to further doses of pediatric pertussis-containing vaccine when occurring within 48 hours of a dose

Answer 23

1. Temperature 40.5 C or higher
2. Hypotonic, hyporesponsive episode
3. Persistent inconsolable crying for 3 hr
4. Seizure with or without fever within 3 days

Question 24

Two conditions that are temporary precautions to administering measles- and varicella-containing vaccines

Answer 24

1. Moderate or severe acute illness

2. Recent administration of an antibody-containing blood product

Question 25

Children aged __ should receive pediatric dose of diphtheria vaccine

Answer 25

younger than 7 yr

Question 26

Schedule of primary series of diphtheria vaccine and booster dose

Answer 26

primary series: 6-10-14 w and 12 mo (4th dose should follow 3rd dose by no less than 6 months and not before 12 mo) (give a 5th dose if 4th dose is given before 4 yr) booster at 4-6 yr and every 10 yr

Question 27

Schedule of diphtheria vaccination in 7 yr and older

Answer 27

primary series: Td 3 doses, first 2 are 4 weeks apart, 3rd dose is 6-12 mo from 2nd dose

Question 28

Recommended interval between Tdap and Td

Answer 28

5 yr

Question 29

Minimum interval between MRRV doses

Answer 29

3 mo

Question 30

MRRV is approved for what ages?

Answer 30

12 mo-12 yr

Question 31

Infants 6 w-6 mo should receive __ doses of HiB vaccine administered __ apart, followed by a booster dose at __ give at least __ months after the last dose.

Answer 31

3 doses 1-2 months apart Booster at 12-15 mo 2 months after last dose

Question 32

Unvaccinated infants 7-11 mo should receive __ doses of HiB vaccine administered __ apart followed by a booster dose at __ given at least __ from the last dose

Answer 32

2 doses 1-2 months apart Booster at 12-15 months At least 2 months from last dose

Question 33

Unvaccinated children aged 12-14 mo should receive __ doses of HiB vaccine __ apart.

Answer 33

2 doses | 1-2 months apart

Question 34

Previously unvaccinated children aged 15-59 mo should receive how many doses of HiB vaccine?

Answer 34

1 dose

Question 35

Infants born to HBsAg positive mothers should receive first dose of Hep B vaccine within __ after birth and the last dose by __.

Answer 35

First within 12 hr | Last by 6 mo

Question 36

For infants of HBsAg mothers should be tested for HBsAg and anti-HBs at __ to monitor success of therapy

Answer 36

9-18 mo

Question 37

Maximum age for rotavirus vaccine

Answer 37

8 mo

Question 38

Which rotavirus vaccine can be given to patients with latex allergy?

Answer 38

Pentavalent rotavirus

Question 39

Vaccine that cannot be given to people with history of egg anaphylaxis

Answer 39

Influenza vaccine