Immunocompromised Hosts

Question 1

T-cell defects:

Answer 1

Recurrent thrush
P. jiroveci pneumonia
Severe HSV/VZV recurrence

Question 2

Immunoglobulin defects:

Answer 2

Recurrent sinopulmonary infections or bacteremia with encapsulated organisms (Strep pneumo, H. flu)
Chronic GI infections/parasites (Giardia)

Question 3

Complement defects:

Answer 3

Severe, recurrent Neisseria infection

Question 4

Neutrophil defects:

Answer 4

Recurrent cutaneous infections (Staph aureus, GNR, aspergillus, nocardia)

Question 5

Integument defects (i.e., drug abuse):

Answer 5

Recurrent cutaneous infections (Staph aureus, Strep, GNR)

Question 6

Organ and marrow transplant:

Answer 6

CMV, HSV, VZV, candida, P jiroveci

Question 7

HIV/AIDS:

Answer 7

P jiroveci, toxoplasma, MAI, candida

Question 8

High-dose steroids:

Answer 8

P jiroveci