Immunodiagnostics

Question 1

describe direct agglutination

Answer 1

• combination of an insoluble particulate antigen with its soluble antibody
  
  • forms antigen-antibody complex
  • particles clump/agglutinate
• examples:
  
  • bacterial agglutination tests for sero-typing and sero-grouping
    
    • e.g. Vibrio cholerae, Salmonella spp