what are the 2 ways T cells provide help to B cells
1) co-stimulatory signal through ligation of CD40 and CD40L
2) secretion of cytokines which aid in the induction of isotype switching
what are the 5 immunoglobulin classes
IgG
IgA
IgM
IgE
IgD
All B cells begin by making which immunoglobulin
IgM
which immunoglobulins do memory cells produce
IgG
IgA
IgM
IgE
what is isotype switching
Isotype switching is a crucial process that occurs in B cells during their maturation and differentiation, allowing them to produce antibodies of different immunoglobulin classes (isotypes) while maintaining the specificity for the same antigen.