AB memory vs T cell
AB has no real decline
T cell will show some
B cell secondary response
IgA, IgG, high affinity, high somatic hypermutation
As time increases, which 2 thingsa about AB change
Affinity increases and more IgG
When does T cell response peak
About a week and then declines
What 2 things are increased in memory cells and why>
Bcl2 - pro survival
IL-7 receptor (CD127)
Memory cells can become
Central or effector memory cells
Mucosal immunity - intestines
More microbiota in large Peyers patches Paneth cells TLRs Layer of mucous T reg cells produce IL-10 and TGFBeta
Paneth cells found in
Crypts
Lymphoid gut tissue drains to
Mesenteric lymph nodes
Lamina propria
T cell rich area of the gut
Dendritic cells of the gut
Extend across the epithelial layer to capture antigen from the lumen of the gut