Immunology

Question 1

What is the primary lymph node drainage site for these anatomic locations?

1. Upper limb, lateral breast
2. Stomach
3. Duodenum, jejunum
4. Sigmoid colon
5. Rectum (lower portion above the pectinate line)
6. Anal canal (below pectinate line)
7. Testes
8. Scrotum
9. Thigh
10. Lateral side of dorsum of foot

Answer 1

1. Axillary
2. Celiac
3. Superior mesenteric
4. Colic –> inferior mesenteric
5. Internal iliac
6. Superficial inguinal
7. Para-aortic superficial and deep plexuses
8. Superficial inguinal
9. Superficial inguinal
10. Popliteal

Question 2

Antigen markers

1. CD1
2. CD3
3. CD4
4. CD8
5. CD10
6. CD16
7. CD20
8. CD21
9. CD45
10. CD56
11. CD15/CD30+
12. CD5+

Answer 2

1. Cortical thymocytes (not mature T cells), Langerhans histiocytes
2. All T cells
3. Helper T cells, or myocsis fungoides/Sezary syndrome
4. Cytotoxic T cells
5. ALL “Calla antigen”
6. NK cells, neutrophils, monocytes, macrophages
7. B cells
8. B cells, EBV receptor, aka complement receptor 2
9. All leukocytes
10. NK cells
11. Reed-Sternberg cells (and usually CD20/CD45 negative)
12. Mantle cell lymphoma