Immunology

Question 1

wt type of hypersensitivy rxn will cause granulomas?

Answer 1

Type IV

Question 2

wt cells do MHC class 1 activate?
2?

Answer 2

1 = CD8
2 = CD4

Question 3

immune mediator that activated macrophages?

wt releases it?

Answer 3

INF- gamma

Th1 release

Question 4

drug that inhibits calcineurin and thus T-cell activation via IL-2?
major AE?
3 things it txs?

Answer 4

Cyclosporine
Nephrotoxicity

transplant rejection
Rheumatoid arthritis
psoriasis

Question 5

wc Ig can be produced in absence of CD4 cells? how does this relate to HIV?

Answer 5

IgM

it is main Ig bc lack of CD4 cells