Immunomodulators

Question 1

Cyclosporine is approved in Humans for what?

Answer 1

1. Prevention of Organ transplant rejection.

Question 2

Cyclosporine has been used to treat what immune mediated diseases?

Answer 2

1. Uveitis
2. Grave’s disease
3. Psoriasis
4. Pemphigus

Question 3

Cyclosporine Clinical Use

Answer 3

1. Ophthalmic application (Kerato-Conjunctivitis Sicca) in dogs
2. Atopic dermatitis in dogs.

Question 4

Cyclosporine Side Effects

Answer 4

1. V/D
2. Decreased Appetite
3. Weight loss
4. Nephrotoxicity and Hepatotoxicity

Question 5

Metronidazole has what three properties?

Answer 5

1. Antibacterial
2. Antiprotozoal
3. Immunosuppressive

Question 6

Metronidazole can be used with what to enhance its effects

Answer 6

corticosteroids

Question 7

Metronidazole Clinical use

Answer 7

1. Lymphocytic- plasmacytic enteritis in dogs
2. Giardiasis
3. Anaerobic bacteria infections

Question 8

Metronidazole Side Effects

Answer 8

1. GI upset
2. Neurologic disturbances
3. Hepatotoxicity
4. Lethargy

Question 9

Oclacitinib common name

Answer 9

Apoquel

Question 10

What is Oclacitinib used to treat

Answer 10

Atopic dermatitis and associated pruritus in dogs at least 12months of age