What is the mode of action of the implant?
Progestogen release:
Prevents ovulation
Cervical thickening
Thinning of endometrium
What is the failure rate of nexplanon?
0.05%
What reduces effectiveness of implant
Enzyme inducers
When to initiate implant?
Can be put in at any time, but need to make sure patient is not pregnant.
Works immediately if within first 5 days of cycle, otherwise use condom for 7 days.
Can be put in within first 21 days postpartum - otherwise condom for 7 days.
Safe in breastfeeding
What reduces effectiveness of implant
Enzyme inducers: Anti-epileptics Anti-retrovirals St John's wort Some TB medication (rifabutin and rifampicin)
Side effects of implant?
Irregular, light or heavy periods in first year.
Amenorrhea is a common side effect.
Headaches
Acne