Inflammation

Question 1

Tissue reaction to injury by physical or chemical agents

Answer 1

Inflammation

Question 2

Inflammation involves __________ and __________ response by the tissues of the body in response to injury

Answer 2

Cellular response

Vascular response

Question 3

Cardinal Signs

Rubor; \_\_\_\_\_\_\_\_\_
Calor: \_\_\_\_\_\_\_\_\_
Dolor: \_\_\_\_\_\_\_\_
Tumor: \_\_\_\_\_\_\_\_\_
Function Laesa: \_\_\_\_\_\_\_\_\_

Answer 3

Cardinal Signs

Rubor; Redness
Calor: Heat production (Hypermia)
Dolor: Pain
Tumor: Swelling
Function Laesa: Loss of function

Question 4

Mechanism in the Vascular Response

Answer 4

1. Increase release of Histamine
2. Vasodilation
3. Increase blood Flow
4. Rubor and Calor
5. Increase capillary permeability
6. Plasma leakage to tissue
7. Tumor and Dolor

Question 5

Mechanism in Cellular Response

Answer 5

1. 30 - 60 mins - PMNs
2. Peak in 16-18 hrs - Macrophages
3. APRs: CRP/Serum amyloid > AAP/Fibrinogen > Haptoglobin > Ceruloplasmin/C3

Question 6

Mechanism in Repair

Answer 6

Increase Fibroblast proliferation

1. Total repair
2. Abcess/Loss of function
3. Granuloma

Question 7

Pain

Answer 7

Dolor

Question 8

Heat

Answer 8

Calor

Question 9

Tumor

Answer 9

Swelling

Question 10

Dolor

Answer 10

Pain

Question 11

Vascular response (vasodilation) is initiated by through release of ___________

Answer 11

Histamine

Question 12

Migrate 30-60 minutes in the site of injury

Answer 12

PMNs

Question 13

Dominant cells in acute stage

Answer 13

PMNs

Question 14

Macrophage peak hours in inflammation

Answer 14

16-18 hrs

Question 15

APRs which responds in 24 hrs

Answer 15

Serum amyloid A
AAP
Fibrinogen
Haptoglobin

Question 16

Most potent APRs that respond within 6-10 hrs

Answer 16

CRP

Question 17

APRs that responds 48-74 hrs

Answer 17

Ceruloplasmin C3

Question 18

APRs increased in 1000x

Answer 18

CRP

Serum amyloid A

Question 19

APRs increased 2-5x

Answer 19

AAP

Fibrinogen

Question 20

APRs increased 2-10x

Answer 20

Haptoglobin

Question 21

APRs increased 2X

Answer 21

C3

Ceruloplasmin