Inflammation

Question 1

5 signs of inflammation

Answer 1

1. pain
2. redness
3. heat
4. swelling
5. loss of function

Question 2

Abscess

Answer 2

localized area of inflammation w/ exudate (antibiotics don’t help, surg to remove)

Question 3

Ulcer

Answer 3

inflammation in epitheial layer: skin or GI tissue

Question 4

Keloid

Answer 4

abnormal healing due to excess collagen causing scar tissue in tumor-like mass

Question 5

Granuloma

Answer 5

chronic inflam leads to lesions of macrophages (infection)

Question 6

Dehiscence

Answer 6

partial/total seperation of wound due to stressors

Question 7

Evisceration

Answer 7

Wound completely seperates, severe, (look for high fluid)

Question 8

Fibrous tissue repair

Answer 8

-connective tissue: new cells and blood supply

Question 9

Scar Tissue

Answer 9

low blood flow, scars no new functioning cells

Question 10

Wound Healing Phases:

Answer 10

1. Inflammatory: starts w/ injury: vasoconstrict, then vasodilate plateltes form clots and phagcytosis
2. Proliferation Phase: day to weeks : granulation tissue forms, collagen, new capillares, wound contracts, new epithelal cells
3. Maturation Phase: weeks to months: Collagen formed/removed to increase strength of wound

Question 11

Acute Inflammation Vs Chronic

Answer 11

-acute: ST, rapid onset
-Chronic: LT, typically due to infections, scar tissue

Question 12

3 outcomes of acute inflammation

Answer 12

1. Resolves
2. Progresses to cronic
3. Necrosis/scaring/fluid

Question 13

Vascular Stage of Acute Inflam

Answer 13

1. high blood flow and vasodilation leads to vascular permability -> swelling, pain loss function (acts to dilute chemicals)

Question 14

Cellular Stage of Acute Inflam

Answer 14

1. Margination of WBCs
2. endothelium
3. Chemotxis (cells migrate to skin)
4. Activation and phagocyotsis

Question 15

Local Inflammation

Answer 15

redness, warmth, pain, swelling, heat, loss of function @ site of injury

Question 16

Systemic Inflammation

Answer 16

fever, high WBCs, fibrongen, fatigue, headache, lethargy, high HR (affects whole body)

Question 17

Factors Affecting Wound Healing

Answer 17

1. age
2. circulation/oxygen
3. nutrition/fluid
4. immune response
5. infection
6. chronic disease
7. meds

Question 18

Symps of Fever

Answer 18

anorexia, headache, fatigue, high HR, dehydration, confusion (part of systemic inflam)

Question 19

Intermittent Fever

Answer 19

temp returns to normal once during 24 hours

Question 20

Remittent

Answer 20

temp doesn’t return to normal and varies few degrees in either direction

Question 21

Sustained

Answer 21

temp higher than normal w/ minimal variation

Question 22

Relapsing Fever

Answer 22

one of more fevers w/in a few days