Inflammation Flashcards

(41 cards)

1
Q

What is Crohn’s Disease characterized by?

A

Subacute and chronic inflammation of the GI tract wall that extends through all layers

Most commonly occurs in the distal ileum and ascending colon.

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2
Q

What are the common age ranges affected by Crohn’s Disease?

A

Ages 15 to 40 years

Younger individuals are predominantly affected.

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3
Q

What is the pathophysiology of Crohn’s Disease?

A

Begins with crypt inflammation and abscesses, leading to small, focal ulcers that deepen into characteristic cobblestone appearance

Fistulas, fissures, and abscesses may form as inflammation extends.

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4
Q

What is Ulcerative Colitis?

A

A chronic ulcerative and inflammatory disease of the mucosal and submucosal layers of the colon and rectum

Characterized by unpredictable periods of remission and exacerbation.

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5
Q

What are the clinical manifestations of Ulcerative Colitis?

A
  • Diarrhea (10-20 stools/day)
  • Blood, mucus, and pus in stool
  • Left lower quadrant cramping and pain
  • Urgent need to defecate/tenesmus
  • Fever
  • Vomiting
  • Anemia
  • Fatigue, weight loss
  • Hypovolemia
  • Nutritional deficits
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6
Q

What laboratory tests are used for IBD?

A
  • CBC
  • Serum albumin
  • ESR
  • Electrolyte panel
  • Iron and vitamin B12
  • Folic acid
  • pANCA (increased with UC)

Stool studies include cultures, ova and parasites, and occult blood of stool.

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7
Q

What are the diagnostic tests for IBD?

A
  • Sigmoidoscopy
  • Colonoscopy/capsule endoscopy
  • Upper GI, Barium enema
  • Abdominal x-ray
  • Rectal biopsy
  • CT scan and MRI
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8
Q

What is the etiology of Inflammatory Bowel Disease (IBD)?

A

An autoimmune disease involving an immune reaction to a person’s own intestinal tract

Triggered by environmental factors, genetic predisposition, and altered immune response.

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9
Q

What are common surgical indications for bowel diversions?

A
  • Disease
  • Injury
  • Cancer
  • Inflammatory Bowel Disease
  • Ulcerative Colitis
  • Crohn’s Disease
  • Diverticulitis
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10
Q

What is diverticulitis?

A

Inflammation of diverticula which may result in perforation into the peritoneum, causing abscesses, fistulas, and bleeding

Can be acute or chronic.

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11
Q

What are the clinical manifestations of diverticulitis?

A
  • Acute pain in LLQ
  • Constipation
  • Nausea
  • Fever
  • Leukocytosis
  • ABD tenderness, palpable mass (with abscess)
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12
Q

What are the preferred imaging tests for diverticulitis?

A
  • CT scan with oral contrast
  • Colonoscopy
  • Barium enema
  • Sigmoidoscopy when suspecting IBD or cancer
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13
Q

What are the goals of pharmacological management in IBD?

A

To induce and maintain remission

Includes using aminosalicylates, antimicrobials, corticosteroids, immunomodulators, and biologic therapies.

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14
Q

What are the complications associated with Ulcerative Colitis?

A
  • Hemorrhage
  • Abscess formation
  • Colonic distention leading to Toxic megacolon
  • Malnutrition from malabsorption
  • Fluid and electrolyte imbalance
  • Bowel obstruction and strictures
  • Bowel perforation leading to peritonitis
  • Increased risk of colon cancer
  • Arthritis and extraintestinal disorders
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15
Q

What is the management for a patient with a colostomy?

A
  • Diet education
  • Care of ostomy
  • Expectations regarding stoma
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16
Q

What are the signs of a potential complication post-laparoscopic cholecystectomy?

A
  • Bleeding
  • Nausea
  • Vomiting
  • Increasing pain
  • Distention of abdomen
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17
Q

What is the typical dietary management for a patient with diverticulitis?

A

High fiber diet, low fat

Stool softeners and anticholinergics may also be used.

18
Q

What are the nursing interventions for managing TPN?

A
  • Confirming placement
  • Monitoring blood glucose levels
  • Two RN check
  • Bag is good for 24 hours
  • Filter usage
19
Q

What is total parenteral nutrition (TPN)?

A

IV solutions providing more than normal caloric intake necessary for patients with malnutrition or malabsorption

Each bag may have approximately 2500 calories over 24 hours.

20
Q

What is the pathophysiology of diverticulosis?

A

Diverticula form when the mucosal and submucosal layers of the colon herniate through the muscular wall due to high intraluminal pressure, low volume in the colon, and decreased muscle strength

Bowel contents can accumulate and decompose, causing inflammation.

21
Q

What are the dietary restrictions for chronic Ulcerative Colitis?

A
  • Avoid milk products
  • Avoid pepper
  • Avoid caffeine
  • Avoid alcohol
  • Avoid raw vegetables and fruits
  • Avoid cold foods
22
Q

When can bandages be removed after surgery?

A

The day after surgery

Followed by the ability to shower.

23
Q

What signs should be reported after surgery?

A

Loss of appetite, vomiting, increasing pain, distention of abdomen, bile-colored drainage

These are indicators of potential complications.

24
Q

What is a possible dietary requirement post-surgery?

A

Low-fat diet for several weeks

This may be necessary after gallbladder removal.

25
What is the surgical therapy for cholecystitis?
Open cholecystectomy ## Footnote Removal of gallbladder through right subcostal incision.
26
What should be monitored post-operatively?
Vital signs, surgical incision sites, signs of infection ## Footnote Pain management and ambulation are also important.
27
What are clinical manifestations of cholecystitis?
Indigestion, moderate to severe pain, fever, leukocytosis, nausea, vomiting, restlessness, jaundice, dark amber urine, clay-colored stools ## Footnote These symptoms may vary in intensity.
28
What are the risk factors for cholelithiasis?
Gender, age, obesity, estrogen, ethnicity, familial tendency, frequent changes in weight, diabetes, sedentary lifestyle ## Footnote These factors increase the likelihood of gallstone formation.
29
What is the most common bacteria associated with cholecystitis?
E. coli ## Footnote Other factors may include torsion and cystic duct obstruction.
30
What is diverticulosis?
Multiple diverticula without inflammation ## Footnote Diverticula are sac-like herniations in the bowel lining.
31
What is diverticulitis?
Infection and inflammation of one or more diverticula ## Footnote This condition can lead to complications if untreated.
32
What is the purpose of a T-tube?
Ensures patency of the common bile duct and allows excess bile to drain ## Footnote It is used post-surgery for gallbladder procedures.
33
What is the pathophysiology of GERD?
Reflux of stomach contents back into the esophagus due to relaxation of the lower esophageal sphincter ## Footnote Severity depends on frequency, contents, and gastric emptying.
34
What are common clinical manifestations of GERD?
Pyrosis, dyspepsia, dysphagia, regurgitation, sore throat, chronic cough ## Footnote Symptoms can vary in intensity and duration.
35
What dietary factors can weaken the LES in GERD?
Chocolate, peppermint, fried foods, coffee, alcohol, large meals ## Footnote These can exacerbate GERD symptoms.
36
What is the first-line pharmacological therapy for GERD?
Antacids ## Footnote They neutralize stomach acid and provide symptom relief.
37
What are the diagnostic tests for acute pyelonephritis?
UA, urine culture and sensitivity, CBC, ultrasound or CT scan ## Footnote These tests help confirm the diagnosis.
38
What are the clinical manifestations of acute gastritis?
Anorexia, rapid onset of epigastric pain, nausea, vomiting, hiccupping ## Footnote Symptoms can vary based on severity.
39
What medications are used to treat H. pylori infection?
Antibiotics such as Amoxicillin, Biaxin, Flagyl, along with proton pump inhibitors ## Footnote Treatment is essential for chronic gastritis caused by H. pylori.
40
What are common risk factors for gastritis?
Aspirin, NSAIDs, alcohol, spicy foods, H. pylori infection ## Footnote Physiological stress and smoking are also contributing factors.
41
What is the priority assessment for a client with gastritis?
Bleeding ## Footnote Monitoring for signs of hemorrhage is crucial.