Vascular Response
Transient vasoconstriction prolonged vasodilation ↑ hydrostatic pressure ↑ blood flow Opening of capillary beds ↑ Increased vascular permeability endothelium retract Leaking of plasma Oedema formation Haemoconcentration → stasis
Cellular Response
Neutrophils monocytes → macrophages through the endothelial gaps → diapedesis chemotaxis Neutrophils chemotactic chemicals.
Phagocytosis
chemotaxis engulfment phagosome formation fusion → phagolysome digestion by lysosomal enzymes
Lymphatic drainage
lymphatic vessels open assisting excessive fluid drainage → inflammatory products → remaining antigens
antigen presenting cells present to immune system
inflammation
healthy tissue responds to injury to destroy and remove foreign substance
first 6-8 hours
factor cause tissue damage
injury-physical/thermal/radiation/electrical/chemical
infection
infraction
immmune response