Gene
A sequence of DNA nucleotides that controls the formation of a single polypeptide . A unit of inheritance
Inheritance
Transmission of traits from one generation to the next
Alleles
Different form of the same gene
Occupy the same relative position on a pair of homologous chromosomes
Genotype
Combination of alleles for a particular gene
Phenotype
expressed trait
Homozygous
Having two identical alleles of a particular gene
Heterozygous
Having two different alle,es of a particular gene
Codimnance
Both alleles express themselves in the heterozygote, which has a phenotype intermediate between that of its pure bred parents
Variation
Difference in traits between Individuals of the same species
Discontinuous
Clear cut phenotypes
Controlled by one or few gens
Genes do no show additive effect
Unaffected by environmental conditions
Continuous
Range of phenotypes
Controlled by many genes
Genes show additive effect
Affected by environmental conditions
Some source of genetic variation
Meiosis
Random fertilisation
Mutation
Mutation
Change in sequence of genes or in chromosome number
Albinism
Recessive gene mutation
Absence of pigment in skin hair and eyes
Sensitive to light and burnt easily
Sickle cell anemia
Gene mutation > result in change in structure of gene > change in sequences of bases
Characteristics : encodes haemogoblin protein in RBC
Phenotype: ppl who are homozygous recessive have abnormal haemogoblin in RBC > oxygen council in blood decrease > RBC become sickle shakes
Sickle shaped cells
Lose ability to transport oxygen .
Fragile sticky, stuck in narrow blood vessels > block flow of oxygen > fatal
Natural selection
Process in which organism with desireable genes and characteristics are selected or favoured to survive and pass on their genes to their offspring
Evolution
Gradual change I’m inheritable characteristics of a population over time
Evolution by natural selection
Variation and competition for survival
Survival of fitest
Reproduction and passing down favourable genes
How Mendel conducted his monohynrid experiment using pea plants. ( 3 steps )
Why does observed ratio often differ from expected ratio
Differentiating dominant and recessive
If person has two DIFFERENT alleles, allele that express itself is called the DOMINNAT ALLELE, while other is called the recessive allele
How can a recessive allele express itself
When person has BOTH recessive alleles in the gene ( e.g person with two alleles for single eyelid > have single eyelid )
What do you use do describe an organism with two dominant alleles for a gene
That organism is homozygous dominant for the trait / gene