Injectable Anesthetics

Question 0

The Barbiturate drugs

Answer 0

Thiopental
Pentobarbital
Phenobarbital

Question 1

What are the 3 classes of injectable anesthetics?

Answer 1

Barbiturates
Non-Barbiturate/Hypnotics
Dissociatives

Question 2

The Non-Barbiturate drugs

Answer 2

Propofol

Etomidate

Question 3

The Dissociative drugs

Answer 3

Ketamine

Tiletamine

Question 4

Can injectable anesthetics produce unconsciousness when given alone?

Answer 4

Yes

Question 5

Can injectable anesthesia provide analgesia or muscle relaxation?

Answer 5

No

Question 6

Barbiturates are derivatives of this acid

Answer 6

Barbituric acid

Question 7

This class of injectable anesthetic is controlled

Answer 7

Barbiturates

Question 8

This class of injectable anesthetic does not have a reversal agent

Answer 8

Barbiturates

Question 9

The classes of Barbiturates are based on this

Answer 9

Duration of action

Question 10

Drug with Ultra short Duration of action

Answer 10

Thiopental

Question 11

Drug with short Duration of action

Answer 11

Pentobarbital

Question 12

Drug with long-acting Duration of action

Answer 12

Phenobarbital

Question 13

Which barbiturates are no longer used as anesthetics?

Answer 13

Most intermediate and long acting

Question 14

What are the 2 sub classes of Barbiturates based on chemical structure?

Answer 14

Oxybarbiturates

Thiobarbiturates

Question 15

Which drugs are Oxybarbiturates?

Answer 15

Phenobarbital
Pentobarbital
Methohexital

Question 16

Which drugs are Thibarbiturates

Answer 16

Thiopental

Thiamylal

Question 17

Which is the only barbiturate used in sx?

Answer 17

Thiopental

Question 18

Which barbiturate is used as an anticonvulsant?

Answer 18

Phenobarbital

Question 19

This class mimics GABA

Answer 19

Barbiturates

Question 20

This class depresses impulses to cerebral cortex

Answer 20

Barbiturates

Question 21

Factors that affect potency, onset, and duration of action of barbiturates

Answer 21

Ionization
Protein binding
Lipid solubility

Question 22

Non-polar form of barbiturate drug passes through this

Answer 22

Cell membrane

Question 23

Acidosis increases this

Answer 23

Non-ionized form of the drug

Drug amounts to the brain

Question 24

What should be done to the dose of a barbiturate if given to an acidotic animal?

Answer 24

Lower dose

Question 25

Protein binding drugs travel in this

Answer 25

In blood bound to a protein

Question 26

An unbound drug can enter here

Answer 26

Brain

Question 27

This results in more free drug

Answer 27

Hypoproteinemia

Question 28

If hypoproteinemia occurs, normal drug (barbiturate) dose may actually produce this

Answer 28

Prolonged unconsciousness or death

Question 29

What is lipid solubility?

Answer 29

The tendency of the drug to dissolve in fats, oils, and lipids

Question 30

Lipid solubility affects this

Answer 30

The ability to penetrate the cell membrane fatty layer

Question 31

High solubility of barbiturates results in this drug

Answer 31

Ultra-short acting | Rapid tissue redistribution

Question 32

Moderate solubility of barbiturates results in this drug

Answer 32

Short-acting

Question 33

Which acting type (ultra short, short, long acting) drug is metabolized by the liver

Answer 33

Short-acting

Question 34

Which acting type (ultra short, short, long acting) drug is metabolized by the kidneys

Answer 34

Long acting

Question 35

Low lipid solubility results in this drug

Answer 35

Long acting

Question 36

Thiopental is given this route

Answer 36

IV

Question 37

You should not give repeated doses of this drug

Answer 37

Thiopental

Question 38

What are the effects of barbiturates on dogs with little fat?

Answer 38

Prolonged recovery | Drug lasts longer on the CNS

Question 39

Which category of drugs an cause sloughing of the tissues if given outside the vein?

Answer 39

Barbiturates

Question 40

The solution to pollution is what?

Answer 40

Dilution

Question 41

Chronic admin. of phenobarbital leads to this

Answer 41

Increased activity of the enzyme MFO, leading to tolerance

Question 42

MFO

Answer 42

Mixed Function Oxidase

Question 43

Don't use Thiopental is this is present

Answer 43

Precipitate

Question 44

Avoid use of this drug in sight hounds

Answer 44

Thiopental

Question 45

Pentobarbital is largely replaced by this drug

Answer 45

Propofol